#Olive leaf extract trial

Despite this, many products on the market place a sole emphasis specifically on the levels of oleuropein the product contains. This synergistic effect highlights the importance of comparing total biophenol content, rather than just individual compounds in isolation. Research suggests that the health effects associated with OLE are likely related to bioactives working in a synergistic manner.

#Olive leaf extract trial

In a 2015 clinical trial a 20mL daily dose of OLE standardised to 136mg oleuropein per day reduced daytime and 24hr systolic and diastolic pressures in pre-hypertensive patients, and also reduced plasma total cholesterol, LDL cholesterol and triglycerides. In-vitro and in-vivo research has shown that OLE has potential antiviral activity, and positively influences various cardiovascular risk factors including inflammation, hypertension, vascular function, and blood lipids. OLE is a natural antioxidant with a range of pharmacological actions. Whilst the main constituents are oleuropein and hydroxytyrosol, olive leaf also contains a large number of other biophenols including p-coumaric acid, oleacein, luteolin and many others. Olive leaf extract is a herbal medicine derived from the olive leaf, containing an abundance of bioactive compounds. OLE made from fresh leaves instead of dried leaves tends to have higher oleuropein levels and lower hydroxytyrosol levels.Practitioner-only products were not necessarily stronger than over-the-counter products, and did not make label statements as to the content of any bioactives.There was a 35-fold variation between the product with the lowest and the product with the highest levels of oleuropein, and an almost 5-fold variation in total biophenols.New research showed there was a significant difference in the phytochemical profile of OLE in different products.This research aimed to evaluate and compare the chemical profile of different OLE products on the Australian market.Olive leaf extract (OLE) in liquid form is sold both over-the-counter, and to health professionals only for dispensing in their clinics.